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Ablation of atrial fibrillation
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Ablation of atrial fibrillation : ウィキペディア英語版
Ablation of atrial fibrillation
The ablation of atrial fibrillation is an invasive technique that is used in the treatment of Atrial fibrillation (AF in the UK or Afib in the US), one of the most common cardiac arrhythmias. Ablation is the removal or melting away of an unwanted structure or tissue. Ablation of atrial fibrillation can be accomplished with different techniques; the most established approach is via radiofrequency ablation around the pulmonary veins, which are the veins that bring oxygenated blood from the lungs back to the upper chambers or atria, in the left side of the heart.
==History==

In 1987, James L. Cox introduced an open-heart surgical procedure which has been subsequently established as capable of curing Atrial Fibrillation. This procedure was originally called the Maze procedure. It consists in a series of incisions and sutures that create many electrically isolated compartments in the atria. In one of its latest designs, it is called Maze IV.〔Ralph J. Damiano, Jr and Marci Bailey. The Cox-Maze IV procedure for lone atrial fibrillation MMCTS (2007) 2007: mmcts.2007.002758 doi:10.1510/mmcts.2007.002758 published online January 1, 2007. http://mmcts.oxfordjournals.org/content/2007/0723/mmcts.2007.002758.full〕 Maze IV, as opposed to Maze III, utilizes radiofrequency or cryoablation and is performed with a medial sternotomy or a lateral thoracotomy and only two small incisions in the atrial muscle. A minimally invasive version, or Minimaze has also been developed.
Specialists in cardiac electrophysiology attempted to replicate the Maze procedure results using catheters advanced via the groin or neck veins, and therefore no incisions, as early as the late 1980s. Only in the 1990s the pioneering work of Michel Haïssaguerre's group focused on the role of the pulmonary veins as the trigger of Atrial Fibrillation.〔Jais P, Haissaguerre M, Shah DPDC et al. A focal source of atrial fibrillation treated by discrete radiofrequency ablation. Circ 1997;95:572-76〕 More recently, circumferential ablation around the pulmonary veins has become the preferred approach and additional focal sources outside the pulmonary veins have been described in specific groups of patients, such as those affected by persistent or chronic atrial fibrillation,〔Left Atrial Appendage: An Underrecognized Trigger Site of Atrial Fibrillation. Luigi Di Biase, MD; J. David Burkhardt, MD; Prasant Mohanty, MBBS, et al. Circulation. 2010;122:101-102〕 patients with sleep apnea and obesity, older female patients, patients with a weak heart muscle (low left ventricular ejection fraction) and patients with microscopic scars in the left atrium.

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